MAGEA6 antibody

Catalog No. ABIN7116158

The Rabbit Polyclonal anti-MAGEA6 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect MAGEA6 in samples from Human and Mouse.

Quick Overview for MAGEA6 antibody (ABIN7116158)

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MAGEA6 Antibody

Purpose: MAGEA6 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: melanoma antigen family A, 6

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MAGEA6

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Alternative Name: MAGEA6

Background:

Synonyms: Melanoma-associated antigen 6|Cancer/testis antigen 1.6 (CT1.6)|MAGE-6 antigen|MAGE3B antigen|MAGEA6|MAGE6

Background: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.

Molecular Weight: 66-70 kDa

Gene ID: 4105

UniProt: P43360